| 논문 및 연구활동 |
- 연구활동(주요논문)
-
[논문]
정효재, 김은하, 박기동, 윤성화, 국, 조덕연, 한준혁, 박주영,
Synthesis of 1-(4-(dimethylamino)phenyl)-3,4-diphenyl-1H-pyrrole-2,5-dione analogues and their anti-inflammatory activities in lipopolysaccharide-induced BV2 cells
, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
, No.92
, pp.1
-6
(Aug, 2023)
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[논문]
윤성화, 김은하, 이은화, 고현명, 백하연, 조덕연, 최동국, 박주영,
Synthesis of 4-(3-oxo-3-phenylpropyl)morpholin-4-ium chloride analogues and their inhibitory activities of nitric oxide production in lipopolysaccharide-induced BV2 cells
, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
, pp.127780
-127780
(Mar, 2021)
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[논문]
이혜경, 박주영, 윤성화, 김승우, 김일두 , 이한비 , 이자경,
Anti-Inflammatory and Neuroprotective Effects of DIPOPA (N,N-Diisopropyl-2-Oxopropanamide), an Ethyl Pyruvate Bioisoster, in the Postischemic Brain
, NEUROTHERAPEUTICS
, Vol.16
, No.2
, pp.523
-537
(May, 2019)
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[논문]
서명원, 김승주, 김주현, Jisook Kwon, Myongjae Lee, 윤성화,
Characterization of Linagliptin–Ferulic Acid Cocrystal with Improved Thermal and Photostability
, BULLETIN OF THE KOREAN CHEMICAL SOCIETY
, Vol.40
, pp.453
-456
(Mar, 2019)
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[논문]
박주영, 신한호, 한지혜, 노준기, 김기우, 성제경, 손동휘, 김욱, 윤성화,
A novel peripheral cannabinoid 1 receptor antagonist, AJ5012, improves metabolic outcomes and suppresses adipose tissue inflammation in obese mice
, FASEB JOURNAL
, Vol.33
, No.3
, pp.4314
-4326
(Feb, 2019)
- 국제학술논문지
-
[논문]
정효재, 김은하, 박기동, 윤성화, 국, 조덕연, 한준혁, 박주영,
Synthesis of 1-(4-(dimethylamino)phenyl)-3,4-diphenyl-1H-pyrrole-2,5-dione analogues and their anti-inflammatory activities in lipopolysaccharide-induced BV2 cells
, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
, No.92
, pp.1
-6
(Aug, 2023)
-
[논문]
윤성화, 김은하, 이은화, 고현명, 백하연, 조덕연, 최동국, 박주영,
Synthesis of 4-(3-oxo-3-phenylpropyl)morpholin-4-ium chloride analogues and their inhibitory activities of nitric oxide production in lipopolysaccharide-induced BV2 cells
, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
, pp.127780
-127780
(Mar, 2021)
-
[논문]
이혜경, 박주영, 윤성화, 김승우, 김일두 , 이한비 , 이자경,
Anti-Inflammatory and Neuroprotective Effects of DIPOPA (N,N-Diisopropyl-2-Oxopropanamide), an Ethyl Pyruvate Bioisoster, in the Postischemic Brain
, NEUROTHERAPEUTICS
, Vol.16
, No.2
, pp.523
-537
(May, 2019)
-
[논문]
서명원, 김승주, 김주현, Jisook Kwon, Myongjae Lee, 윤성화,
Characterization of Linagliptin–Ferulic Acid Cocrystal with Improved Thermal and Photostability
, BULLETIN OF THE KOREAN CHEMICAL SOCIETY
, Vol.40
, pp.453
-456
(Mar, 2019)
-
[논문]
박주영, 신한호, 한지혜, 노준기, 김기우, 성제경, 손동휘, 김욱, 윤성화,
A novel peripheral cannabinoid 1 receptor antagonist, AJ5012, improves metabolic outcomes and suppresses adipose tissue inflammation in obese mice
, FASEB JOURNAL
, Vol.33
, No.3
, pp.4314
-4326
(Feb, 2019)
-
[논문]
박주영, 이해언, 김병욱, 최동국, 윤성화,
Synthesis of Clovamide Analogues That Inhibit NO Production in Activated BV-2 Microglial Cells
, BIOLOGICAL & PHARMACEUTICAL BULLETIN
, Vol.40
, No.9
, pp.1475
-1482
(Sep, 2017)
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[논문]
곽우영, 목희연, 윤성화,
Improved Synthesis of (R)-3-(t-Butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic Acid as a Key Intermediate for the Synthesis of Sitagliptin
, Bulletin of the Korean Chemical Society
, Vol.38
, No.8
, pp.976
-979
(Aug, 2017)
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[논문]
김승우, 박주영, 윤성화, 최규진, 이자경,
Neuroprotective effect of triflusal and its main metabolite, 2-hydroxy-4-trifluoromethylbenzoic acid (HTB), in the postischemic brain
, NEUROSCIENCE LETTERS
, Vol.643
, pp.59
-64
(Mar, 2017)
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[논문]
이혜경, 박주영, 윤성화, 김승우, 김일두, 이한비, 이자경,
Anti-inflammatory and antiexcitoxic effects of diethyl oxopropanamide, an ethylpyruvate bioisoster, exert robust neuroprotective effects in the postischemic brain
, SCIENTIFIC REPORTS
, Vol.7
, pp.42891
-42891
(Feb, 2017)
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[논문]
김승우, 박주영, 윤성화, Lidan Luo, 김일두, 이한비, 이혜경, 이자경,
Robust neuroprotective effects of 2-((2-oxopropanoyl)oxy)-4-(trifluoromethyl)benzoic acid (OPTBA), a HTB/pyruvate ester, in the postischemic rat brain
, SCIENTIFIC REPORTS
, pp.1
-12
(Aug, 2016)
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[논문]
김승우, 김현지, 윤성화, 이혜경, 이자경,
Neuroprotective effect of ethyl pyruvate against Zn2+ toxicity via NAD replenishment and direct Zn2+ chelation
, NEUROPHARMACOLOGY
, Vol.105
, pp.411
-419
(Jun, 2016)
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[논문]
구진모 , 권순정, 박주영, 윤성화, 김유한, 남연주, 남태규, 박규희, 양준근, 이정훈, 정대연, 조경진, 안상미, 최용문,
Discovery, Optimization, and Biological Evaluation of Sulfonamidoacetamides as an Inducer of Axon Regeneration
, JOURNAL OF MEDICINAL CHEMISTRY
, Vol.59
, No.10
, pp.4676
-4687
(May, 2016)
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[논문]
박주영, 권순정, 김병욱, 이자경, 최동국, 윤성화,
Syntheses of Ethyl Pyruvate’s Bioisosteres Inhibiting Inducible Nitric Oxide Production in Lipopolysaccharide-induced BV2 Cells
, LETTERS IN DRUG DESIGN & DISCOVERY
, Vol.12
, No.7
, pp.591
-596
(Jul, 2015)
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[논문]
김병욱, 박주영, 윤성화, Hemant Kumar, Sandeep Moore, Sushruta Koppula, 김시관, 김인수, 김일웅, 한상돈, 최동국,
alpha-Asarone attenuates microglia-mediated neuroinflammation by inhibiting NF kappa B activation and mitigates MPTP-induced behavioral deficits in a mouse model of Parkinson's disease
, NEUROPHARMACOLOGY
, Vol.97
, pp.46
-57
(May, 2015)
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[논문]
임형우, 박주영, 윤성화, Sandeep More, 김병욱, 박은정, 박정인, 윤요셉, 전세봄, 최동국,
Anti-neuroinflammatory effects of DPTP, a novel synthetic clovamide derivative in in vitro and in vivo model of neuroinflammation
, BRAIN RESEARCH BULLETIN
, Vol.112
, pp.25
-34
(Mar, 2015)
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[논문]
민순, 박주영, 윤성화, Sandeep Vasant Moore, 박신영, 박은정, 전세범, 최동국,
EOP, a Newly Synthesized Ethyl Pyruvate Derivative, Attenuates the Production of Inflammatory Mediators via p38, ERK and NF-κB Pathways in Lipopolysaccharide-Activated BV-2 Microglial Cells
, MOLECULES
, Vol.19
, No.12
, pp.19361
-19375
(Nov, 2014)
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[논문]
강성묵, 박주영, 윤성화, Sandeep Vasant Moore, 김병욱, 박정인, 최동국,
A novel synthetic HTB derivative, BECT inhibits lipopolysaccharide-mediated inflammatory response by suppressing the p38 MAPK/JNK and NF-κB activation pathways
, PHARMACOLOGICAL REPORTS
, Vol.66
, No.3
, pp.471
-479
(Jun, 2014)
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[논문]
박주영, 신영균, 권영배, 김기원, 윤성화,
Syntheses of 7-Substituted α-Cyperone Derivatives for Selective Sigma-1 Receptor over Cannabinoid-1 Receptor Binding Affinities
, BULLETIN OF THE KOREAN CHEMICAL SOCIETY
, Vol.34
, No.11
, pp.3499
-3502
(Nov, 2013)
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[논문]
이혜경, 박주영, 윤성화, Yinchuan Jin, 김승우, 김일두, 이자경,
Anti-inflammatory effects of OBA-09,a salicylic acid/pyruvate ester,in the postischemic brain
, BRAIN RESEARCH
, Vol.1528
, pp.68
-79
(Aug, 2013)
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[논문]
Sandeep Vasant More, 박주영, 윤성화, Hemant Kumar, Sushruta Koppula, 강성묵, 깁병욱, 임형우, 최동국,
Anti-neuroinflammatory Activity of a Novel Cannabinoid Derivative by Inhibiting the NF-κB Signaling Pathway in Lipopolysaccharide Induced BV-2 Microglial Cells
, JOURNAL OF PHARMACOLOGICAL SCIENCES
, pp.119
-130
(Feb, 2013)
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[논문]
박주영, 권순정, 김인수, 명승윤, 최동국, 윤성화,
Simultaneous Measurement of Serotonin, Dopamine and Their Metabolites in Mouse Brain Extracts by High-Performance Liquid Chromatography with Mass Spectrometry Following Derivatization with Ethyl Chloroformate
, BIOLOGICAL & PHARMACEUTICAL BULLETIN
, Vol.36
, No.2
, pp.252
-258
(Feb, 2013)
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[논문]
이현정, 윤성화, 이은화, 김균, 장희라, 권정환,
Enzymatic and microbial transformation assays for the evaluation of the environmental fate of diclofenac and its metabolites
, CHEMOSPHERE
, Vol.87
, No.8
, pp.969
-974
(May, 2012)
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[논문]
정영철, 박주영, 윤성화, 김상열, 김윤성, 맹성호, 박성현, 복유진, 허수현, 진병관,
Cannabinoid Receptor Type 1 Protects Nigrostriatal Dopaminergic Neurons against MPTP Neurotoxicity by Inhibiting Microglial Activation
, JOURNAL OF IMMUNOLOGY
, No.12
, pp.6508
-6517
(Dec, 2011)
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[논문]
이수진, 윤성화, 도경오,
Enhancement of Gene Delivery Using Novel Homodimeric Tat Peptide Formed by Disulfied Bond
, JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
, Vol.21
, No.8
, pp.802
-807
(Aug, 2011)
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[논문]
김현지, 김승우, 이자경, 윤성화,
A simple and sensitive high performance liquid chromatography-electrospray ionization/mass spectrometry method for the quantification of ethyl pyruvate in rat plasma
, BULLETIN OF THE KOREAN CHEMICAL SOCIETY
, Vol.32
, No.4
, pp.1221
-1227
(Apr, 2011)
-
[논문]
정영찬, 박주영, 윤성화, 고혁운, 김상열, 김윤성, 박근우, 박은수, 복의진, 원소연, 정은숙, 진민영, 진병관,
Fluoxetine prevents MPTP-induced loss of dopaminergic neurons by inhibiting microglial activation
, NEUROPHARMACOLOGY
, Vol.60
, pp.963
-974
(Apr, 2011)
-
[논문]
박주영, 임원빈, 김승우, 이자경, 진병관, 윤성화,
Simplified Heterocyclic Analogues of Fluoxetine Inhibit Inducible Nitric Oxide (NO) Production in Lipopolysaccharide (LPS)-Induced BV2 Cells
, Biological and Pharmaceutical Bulletin
, Vol.34
, No.4
, pp.538
-544
(Apr, 2011)
-
[논문]
임원빈, 박주영, John Finn, 최선호, 최성학, 윤성화,
Discovery of Torezolid as a Novel 5-Hydroxymethyl-Oxazolidinone Antibacterial Agent
, EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
, Vol.46
, pp.1027
-1039
(Feb, 2011)
-
[논문]
김승우, 김현지, 윤성화, 김일두, 신주현, 이정은, 한평림, 이자경,
Robust protective effects of a novel multimodal protectant oxopropanoyloxy benzoic acid (a salicylic acid/pyruvate ester) in the postischemic brain
, MOLECULAR PHARMACOLOGY
, Vol.79
, No.2
, pp.220
-228
(Feb, 2011)
-
[논문]
박주영, 박호준, 임원빈, 김승우, 이자경, 윤성화,
Synthesis and Antioxidant Effect of Caffeic Acid Analogues Bearing a Carboxy and Hydroxymethyl Group
, BULLETIN OF THE KOREAN CHEMICAL SOCIETY
, Vol.31
, No.12
, pp.3860
-3863
(Dec, 2010)
-
[논문]
김상현, 권정환, 윤성화,
An improved synthesis of 4'-hydroxydiclofenac
, BULLETIN OF THE KOREAN CHEMICAL SOCIETY
, Vol.31
, No.10
, pp.3007
-3009
(Oct, 2010)
-
[논문]
장다영, 김성수, 김세중, 유승완, 윤성화, 이영돈, 조경기, 김수정, 백선아, 홍영태, 서해영,
The growth of brain tumors can be suppressed by multiple transplantation of mesenchymal stem cells expressing cytosine deaminase
, INTERNATIONAL JOURNAL OF CANCER
, Vol.127
, No.8
, pp.1975
-1983
(Oct, 2010)
-
[논문]
정은숙, 박주영, 윤성화, 박은수, 백형후, 복유진, 정영철, 진병관,
Fluoxetine prevents LPS-induced degeneration of nigral dopaminergic neurons by inhibiting microglia-mediated oxidative stress
, BRAIN RESEARCH
, No.1363
, pp.143
-150
(Sep, 2010)
-
[논문]
손문호, 신영균, 김미경, 김순회, 김하동, 문호상, 박경진, 신창열, 안국준, 양은경, 채유나, 채혜원, 최성현, 윤성화,
Peripherally acting CB1-receptor antagonist: the relative importance of central and peripheral CB1 receptors in adiposity control
, INTERNATIONAL JOURNAL OF OBESITY
, No.34
, pp.547
-556
(Mar, 2010)
-
[논문]
김승우, 김현지, 윤성화, 서지선, 정지영, 한평림, 이자경,
Combination treatment of ethyl pyruvate and aspirin enhances neuroprotection in the postischemic brain
, NEUROTOXICITY RESEARCH
, No.17
, pp.39
-49
(Jan, 2010)
-
[논문]
윤영실, 윤성화, 이창호, 조태섭, 민철기,
N-Methylamine substituted fluoxetine derivatives:New dopamine transporter inhibitors
, ARCHIVES OF PHARMACAL RESEARCH
, Vol.32
, No.12
, pp.1663
-1671
(Dec, 2009)
-
[논문]
류종훈, 윤성화, 김동현, 이승주,
Sub-chronic administration of rimonabant causes loss of antidepressive activity and decrease doublecortin immunoreactivity in the mouse hippocampus
, Neuroscience letters
, Vol.467
, No.2009
, pp.111
-116
(Dec, 2009)
-
[논문]
윤성화, 신영균,
New One-Pot Synthesis of 4-Hydroxybenzaldehyde Derivatives and Picric Acid from 4-Hydroxyphenylglycine with HNO3/H2O
, Bulletin of the Korean chemical society
, Vol.30
, No.11
, pp.2819
-2822
(Nov, 2009)
-
[논문]
이자경, 박주영, 윤성화, 김승우, 서지원, 임채문, 진인찬, 한평림,
Fluoxetine attenuates kainic acid-induced neuronal cell death in the mouse hippocampus
, Brain research
, Vol.2009
, No.1281
, pp.108
-116
(Jun, 2009)
-
[논문]
이자경, 박주영, 윤성화, 김승우, 김채균, 임채문,
Fluoxetine affords robust neuroprotection in the postischemic brain via its anti-inflammatory effect
, Journal of Neuroscience Research
, Vol.87
, No.4
, pp.1037
-1045
(Feb, 2009)
-
[논문]
윤성화, 정효재, 김영수, 박호준, 신영균,
Bioisoster of caffeic aicd: Syntheses of 1-hydroxy-2-pyridone analogues
, BULLETIN of the Korean Chemical Society
, Vol.29
, No.11
, pp.2277
-2280
(Nov, 2008)
-
[논문]
윤성화, 박호준, 신영균, 이해언,
A new route of 5-(N-phenetylamino)salicylic acid derivatives by rapid and selective reduction of the amide group with NaBH4/acetic acid
, Synthetic Communications
, Vol.38
, No.11
, pp.1822
-1829
(May, 2008)
-
[논문]
윤성화, 박호준, 신영균, Suk Bin Kong, 김승우, 김윤정, 이자경,
New peptidic neuroprotectas against NMDA neurotoxicity: Syntheses and biological evaluations of linear complestatin analogs
, LETTERS IN DRUG DESIGN & DISCOVERY
, Vol.5
, No.2
, pp.104
-107
(Mar, 2008)
-
[논문]
윤성화, 박상후, 박호준, 신영균, Bicholas Bodor, Jiaxaing Wu,
Selective reduction of trigonellyl group to the corresponding dihydropyridine in the presence of disulfide group
, Bulletin of the Korean Chemical Society
, Vol.29
, No.2
, pp.479
-482
(Feb, 2008)
-
[논문]
곽병주, 문호상, 안영민, 윤성화, 이해운, 고선영, 권혜진, 김기원, 노지현, 박선미, 변한열, 손선주, 원석준, 윤복선, 이문정, 이영애, 이지윤, 임두순, 임향란, 정준모, 조성익, 조제영,
Marked prevention of ischemic brain injury by Neu2000, an NMDA antagonist and antioxidant derived from aspirin and sulfasalazine
, Journal of Cerebral Blood Flow and Metabolism
, Vol.2007
, No.27
, pp.1142
-1151
(Jun, 2007)
-
[논문]
곽병주, 윤성화, 노지현, 원석준, 유보름, 이영애, 장수현, 정준모, 주천기, 최춘섭,
The Novel Neuroprotective Action of Sulfasalazine through Blockade of NMDA Receptors
, The Journal of Pharmacology and Experimental Therapeutics
, Vol.305
, No.1
, pp.48
-56
(Mar, 2003)
-
[논문]
Nicholas Bodor, 윤성화, Jiaxiang Wu, Whei-Mei Wu,
Synrthesis and biological evaluation of brain-targeted chemical delivery systems of [Nva2]-TRH
, Journal of Pharamcy and Pharmacology
, Vol.54
, No.7
, pp.945
-950
(Jul, 2002)
-
[논문]
윤성화, 김동연, 김수동, 이영애, 남성일, 문호상,
Structural requirements for the neuroprotective effects of aspirin analogues against N-methyl-D-aspartate and zinc ion neurotoxicity
, Journal of Pharmacy and Pharmacology
, Vol.54
, No.7
, pp.935
-944
(Jul, 2002)
-
[논문]
곽병주, 김동현, 김수동, 남성일, 문호상, 이영애, 윤성화,
Structural requirements for the neuroprotective effects of aspirin analogues against N-methyl-D-aspartate and zinc ion neurotoxicity
, JOURNAL OF PHARMACY AND PHARMACOLOGY
, pp.935
-944
(Jul, 2002)
-
[논문]
윤성화, Jiaxiang Wu, Nicholas Bodor,
Synthesis and Brain Targeted Delivery of [Nva2,Pip3]-TRH
, Bulletin of the Korean Chemical Society
, Vol.23
, No.5
, pp.761
-764
(May, 2002)
-
[논문]
강규완, 김은영, 유보름, 윤성화, 문호상, 장수연, 정준모, 한평림,
Attenuation of Zn2+ Neurotoxicity by Aspirin: Role of N-Type Ca2+ Channel and the Carboxyl Acid Group
, Academic Press
, Vol.8
, pp.774
-783
(Oct, 2001)
-
[논문]
곽병주, Bo Rum Ryu, Chang Su-Youne, 강규완, 김은영, 문호상, 윤성화, Choun-Ki Joo, 한평림,
Attenuation of Zn2+ NeuroToxicity by Aspirin: Role of N-Type Ca2+ Channel and the Carboxyl Acid Group
, Neurobiology of Disease
, Vol.8
, pp.744
-783
(May, 2001)
-
[논문]
Nicholas Bodor, 윤성화, Jiaxiang Wu, Laszlo Prokai, Whei-Mei Wu,
Brain-Targeted Chemical Delivery of [Leu2,Pip3]-TRH; Synthesis and Biological Evaluation
, Pergamon Press
, Vol.8
, No.5
, pp.1059
-1063
(Jun, 2000)
-
[논문]
Nicholas Bodor, 윤성화, 황성관, Atilla Juhasz,
Soft Drug 12: Design, Synthesis, and Evaluation of Soft Bufuralol Analogues
, American Chemical Society
, Vol.43
, No.8
, pp.1525
-1532
(Apr, 2000)
-
[논문]
윤성화, 김현숙,
Bioisoster of Capsaicin: Synthesis of 1-Hydroxy-2-pyridone Analogue
, Bulletin of the Korean Chemical Society
, Vol.20
, No.7
, pp.857
-859
(Jul, 1999)
-
[논문]
윤성화, 김동연, 서승기, 이영희, 황성관,
Syntheses of 2-[(3,5-Dimethyl-4-Methoxypyridyl)alkyl)benzothiazodine Derivatives As a Potential Gastric H+/K+-ATPase Inhibitor
, 영국화학회
, Vol.8
, pp.1909
-1912
(Sep, 1998)
-
[논문]
윤성화, 문호상, 최승룡, 황성관, 강성구,
Syntheses and Cytotoxicities of Four Stereoisomers of Muricatacin from D-Glucose
, Bioorgaic and Medicinal Chemistry
, Vol.6
, pp.1043
-1049
(Aug, 1998)
-
[논문]
박규순, 윤성화, 최승룡, 이석우, 이윤석,
Synthesis of Optically Pure (2R,2'R,5R,5'R)-5,5'-Bisiodomethyl-octahydro[2,2']-bifuran from Diethyl D-tartrate: Iodoetherification of (5R,6R)-5,6-Dihydroxy-1,9-decadiene
, Bulletin of the Korean Chemical Society
, Vol.19
, No.1
(Jan, 1998)
-
[논문]
윤성화, 강봉구, 서문호, 윤병선, 이석현, 이재의,
Studies on the Physical properties of Modified Starch-filled HDPE Film
, Journal of Applied Polymer Science
, Vol.60
, pp.1977
-1984
(Mar, 1996)
-
[논문]
서문호, 윤병선, 윤성화, 이석현, 이재의, 정시화,
Studieson the Degradable Polyethyles : Use of Coated Photodegradants with Biopolymers
, Journal of Applied Polymer Science
, Vol.60
, pp.1677
-1685
(Mar, 1996)
-
[논문]
이우영, 김효중, 심원보, 윤성화,
Biscyclophanes. Part 2:Regioselectivity in the Acid-Catalysed Cycloalklation of Benzylbenzylic Alcohol(BBA)
, J.of Chem.Soc.Perkin Trans.(SCI)
, pp.719
-729
(Mar, 1993)
-
[논문]
Nicholas, 윤성화, James.W.S.,
Synthesis and In Vitro Dopaminergic Activity of (2-Aminoethly)-1-hydroxy-2-pyridone Type Dopamine Analogs
, Drug Design and Discovery
, Vol.10
, pp.35
-43
(Mar, 1993)
- 국내학술논문지
-
[논문]
김영수, 김수동, 윤성화,
Effect of Softcapsule Fill Formulation on the Stability and the Disintegration Time of Ginkgo Biloba Extract
, Jouranl of Korean Industrial Engineering Chemistry
, Vol.10
, No.6
, pp.848
-851
(Oct, 1999)
-
[논문]
김영수, 김수동, 윤성화,
연질캅셀 제제 처방이 은행잎 엑스의 안정성 및 붕해 시간에 미치는 영향
, 공업화학
, Vol.10
, No.6
, pp.848
-851
(Aug, 1999)
-
[논문]
윤성화, 문호상, 박정하, 김영수,
A New Route to the Synthesis of Cortodoxon from Progesterone
, Bulletin of the Korean Chemical Society
, Vol.20
, No.2
, pp.229
-231
(Feb, 1999)
-
[논문]
윤성화, 강석구, 문호상,
Synthesis and Cytotoxicity of (-)-(4R,5R)-5-C-(11-Methoxy)muricatacin
, Bulletin of the Korean ChemicalSociety
, Vol.19
, No.9
, pp.1016
-1018
(Sep, 1998)
-
[논문]
윤성화, 김도영, 황성관,
Synthesis of N-[2-(3,5-dimethyl-4-methoxypyridyl)alkyl]oxazolidinone Analogues and Evaluation of Their Proton Pump Enzyme Inhibition
, J. of Korean Pharmaceutical Society
, Vol.41
, No.2
, pp.174
-180
(Apr, 1997)
-
[논문]
윤성화, 황성관, 심원보,
Efficient Synthesis of 2-Acetyl-7-formylbenzofuran and 2-Acetyl-(formylmetyl)benzofuran through the Oxidative Cleavage of Allybenzofuran with Osmium Tetraoxide/Sodium Periodate
, Bull. Korean Chemical Society
, Vol.17
, No.3
, pp.295
-299
(Mar, 1996)
-
[논문]
윤성화, 박규순,
Synthesis & in Vitro Stability Evaluation of 5-(2'-(N-(1-methyl-3'-carbamylphenyl)-n-propyl))aminoethyl)-8-hydroxy-4-methyl carbostyril Deravatives
, 약학회지
, Vol.39
, No.5
, pp.506
-510
(Mar, 1995)
-
[논문]
김영희, 유경수, 윤성화,
Synthesis and Characterization of Poly[5,6-dideoxy-alpha-D-xylo-hex-5-enofuranose-alt(maleic anhydride)]
, Bull.Korean.Chem.Soc
, Vol.15
, No.5
, pp.407
-410
(Mar, 1994)
-
[논문]
윤성화,
신약도안에서의 Biosoterism의 응용
, 화학세계
, Vol.33
, No.8
, pp.576
-579
(Mar, 1993)
- 국제학술발표
-
[학술회의]
김정은, 김욱, 김은하, 윤성화, 윤주환,
Characterization of AJ5012 as a Novel Peripheral Cannabinoid 1 Receptor Antagonist in Mouse Models of Obesity
, 78th Scientific Sessions of American Diabetes Association
(Jun, 2018)
-
[학술회의]
한지혜, 김욱, 노준기, 신한호, 윤성화, 윤주환, 허성은,
Blockade of peripheral cannabinoid 1 receptor attenuates insulin resistance through inhibition of NLRP3 inflammasome activation in diabetic obese mice
, 77th Scientific Session of American Diabetes Association
(Jun, 2017)
-
[학술회의]
한지혜, 김욱, 노준기, 박주영, 신한호, 윤성화,
Blockade of peripheral cannabinoid 1 receptors improves insulin resistance through preventing the activation of NLRP3 inflammasome in white adipose tissue
, 2016 Internationbal Congress on Obesity and Metabolic Syndrome in conjunction with the 45th Annual Scientific Meeting of KSSO
(Sep, 2016)
-
[학술회의]
윤성화, 권순정, 박주영, 박정호, 최동국,
Synthesis and bioogical evaluation of caffeic acid analogues for antioxidant activities
, 2012 Proceedings of International Congress of Korean Fedration of Pharmaceutical Societies
, pp.329
-329
(Apr, 2012)
-
[학술회의]
이은화, 윤성화, 박성훈, 최동국,
Synthesis and Biological Evaluation of 3-Morpholino-1-phenylpropan-1-one Analogues as an Inhibitor of Inducible Nitric Oxide Production in Lipopolysaccharide-Induced BV2 Cells
, 2011 대한약학회 추계 국제학술회의
, pp.250
-250
(Nov, 2011)
-
[학술회의]
박주영, 윤성화, 박성훈, 이은화, 김승우, 이자경,
Synthesis and antioxidant effect of caffeic acid analogues bearing a carboxy and hydroxymethyl group
, the Fall International Convention of the Pharmaceutical Society of Korea
, pp.210
-210
(Oct, 2010)
-
[학술회의]
윤성화, 권정환, 김상현, 박성훈,
An improved procedure for preparation of 4'-hydroxydichlorofenac
, Proceedings of the spring international convention of the pharmaceutical society of korea
(Apr, 2010)
-
[학술회의]
윤성화, 김현지, 이은화, 김승우, 이자경,
Neuroprotective effects of ethyl pyruvate derivatives by transition metal chelation
, The proceedings of the spring international convention of the pharmaceutical society of Korea
(Apr, 2010)
-
[학술회의]
윤성화, 김현지, 이자경,
Retrometaboic approach for the treatment of stroke based on pyruvylsalicylic acid system
, 7th Retrometabolic Based Drug Design and Targeting Conference
, Vol.2009
, No.1
, pp.23
-23
(May, 2009)
-
[학술회의]
윤성화, 박주영,
Synthesis and biological evaluation of oxoacetamide analogues of rimonabant as CB1 cannabionoid receptor ligands
, Medicianl chemistry conference (lead optimization and lead discovery)
, Vol.2009
, pp.31
-31
(Feb, 2009)
-
[학술회의]
이자경, 윤성화, 김승우, 신주현, 임채문, 최경신,
Multi-mechanism baded ethyl pyruvate hybrid compound affords robust neuroprotection in the postischemic brain
, Annual meeting of neuroscience 2008
, Vol.2008
, pp.97
-97
(Nov, 2008)
-
[학술회의]
윤성화, 박상후, 박호준, 정효재, 박정호,
Bioisosteres of Caffeic Acid: Syntheses of 1-Hydroxy-2-Pyridone Analogs
, 대한약학회 2008 제주국제학술대회
, Vol.2008
, pp.262
-262
(May, 2008)
-
[학술회의]
윤성화, 박주영, 임원빈,
Measurement of Dopamine, Their Metabolites and Serotonin by High Performance Liquid Chromatography with Mass Spectrometry Following Derivatization with Ethyl Chloroformate
, 대한약학회 2008 제주국제학술대회
, Vol.2008
, pp.307
-307
(May, 2008)
-
[학술회의]
윤성화, 김현지, 이수진, 신영균,
Method for Quantification of Ethyl Pyruvate by Liquid Chromatography/Electtospray Ionization Mass Spectrometry
, 대한약학회 2008 제주국제학술대회
, Vol.2008
, pp.313
-313
(May, 2008)
-
[학술회의]
이자경, 윤성화, 이해언, 정효재, 김승우, 신주현, 암채문,
The synergistic neuroprotection by ethyl pyruvate and apirin in the postischemic brain
, the Annual meeting of the society for neuroscience
, Vol.2007
, pp.380
-380
(Nov, 2007)
-
[학술회의]
윤성화, 김현지, 김희연, 정효재,
Synthesis and biological evaluations of carbamoyl oxime analogs of the cannabinoid receptor-1 (CB1) antagonist SR141716
, 234th Annual Meeting of American Chemical Society
, Vol.2007
, pp.34
-34
(Aug, 2007)
-
[학술회의]
윤성화, 김희연, 박주영, 신영균, 김기원,
Synthesis and biological evaluations of the cyperone analogs
, The 12th Asian symposium on medicinal plants, spices, and natural products
, Vol.2006
, No.1
, pp.53
-53
(Nov, 2006)
-
[학술회의]
윤성화, 곽병주, 박호준, 신영균, 문호상,
Synthesis and biological evaluations of N-substituted aminosalicylic acid serivatives as novel neuroprotectant agent
, 11th Asian Chemical Congress
, Vol.11
, No.1
, pp.177
-177
(Aug, 2005)
-
[학술회의]
윤성화, 곽병주, 박호준, 이재우, 이영애,
Synthesis and neuroprotective effect of Neu2000 against rat transient ischemic stroke models
, 229th Annual Meeting of American Chemical Society
, Vol.229
, No.1
, pp.202
-202
(Mar, 2005)
-
[학술회의]
윤성화, 신영균, 이재우, 이주영,
New Synthetic method of 3-substituted 4-hydroxy-5-nitrobenzaldehyde and 2-substituted-4,6-dinitrophenol from 3-substituted D-4-hydroxyphenylglycine
, 229th Annual Meeting of American Chemical Society
, Vol.229
, No.1
, pp.519
-519
(Mar, 2005)
-
[학술회의]
윤성화, 곽병주, 박주영, 이주영, 이영애,
Synthesis and biological evaluation of salicylic acid analogues of celecoxib as a new class od selective cyclooxygenase-1 inhibitors
, 229th Annual Meeting of American Chemical Society
, Vol.219
, No.1
, pp.222
-222
(Mar, 2005)
-
[학술회의]
곽병주, 박호준, 신진희, 윤성화, 전정욱, 조성익, 주인수, 임향란,
Neu2000, a new compound with strong antioxidant action and NMDA antagonism, is beneficial against ALS model mice.
, Society for Neuroscience 34th Annual Meeting
, Vol.34
, No.1
, pp.126
-126
(Oct, 2004)
-
[학술회의]
곽병주, B.S Yoon, J.Y Lee, 신영균, 안춘산, 원석준, 윤성화, 조성익, 강순철, 고선영, 임두순,
Neu2000, a novel compound, shows potent neuroprotection against rat ischemic stroke models through multiple mechanisms with wide therapeutic time window
, Society for Neuroscience 34th Annual meeting
, Vol.34
, No.1
, pp.126
(Oct, 2004)
-
[학술회의]
곽병주, J.Y Lee, 권혜진, 윤성화, 노지현, 이영애, 정준모,
NOVEL NEUROPROTECTANT PREVENTING NMDA-, FREE RADICAL-, AND ZINC-NEUROTOXICITY
, Society for neuroscience 34th annual meeting
, Vol.34
, No.1
, pp.126
-126
(Oct, 2004)
-
[학술회의]
박기동, 박형달, 윤성화, 지경수, 신정욱, 이진우,
Chondrogenic Differentiation of a Mesenchymal Stem Cell using a Novel Injectable Thermosensitive Chitosan
, 8th Pacific Polymer Conference
, pp.1
-3
(Nov, 2003)
-
[학술회의]
윤성화, 곽병주, 박호준, 이해언,
Synthesis and neuroprotective effects of the cyclic analogs of complestatin
, 226th ACS national meeting
, pp.291
-291
(Sep, 2003)
-
[학술회의]
윤성화, 곽병주, 박의진, 원석준,
Involvement of mitochondrial reactive oxygen species in the selective vulnerability of somatostatinergic interneurons to kainate
, 32nd annual meeting of society for neuroscience
, pp.1
-1
(Nov, 2002)
-
[학술회의]
윤성화, 곽병주, 남상돈, 박호준, 전보형,
Syntheses and neuroprotective effects of complestatin analogs
, 223rd ACS national meeting
, Vol.2002
, pp.48
-48
(Apr, 2002)
-
[학술회의]
윤성화, 강규완, 곽병주, 박호준, 전보형, 문호상,
Syntheses and Multiple Neuroprotective Effects of Benzylaminosalicylic Acid Derivatives
, 222nd ACS National Meeting
, Vol.2001
, pp.60
(Aug, 2001)
-
[학술회의]
윤성화, 곽병주, 김상남, 김윤정, 김정숙, 남상돈,
Syntheses and Neuroprotective Effects of the Conjugates of 5-(Pentafluorobenzyl)amino Acid with DMVD-FMK Derivatives
, 222nd ACS national Meetings
, Vol.125
, pp.50
-50
(Aug, 2001)
-
[학술회의]
진병관, 곽병주, 김승업, 김진, 류재규, 윤성화, 오영준,
A Novel Neuroprotectant Rescuing Nigral Dopaminergic Neurons From MPP+ Neurotoxicity.
, Society for Neuroscience 30th Annual Meeting
, Vol.26
, No.857.10
, pp.2282
-2282
(Nov, 2000)
-
[학술회의]
곽병주, 유보름, 윤성화, 노지현, 이영애, 장수연, 정준모,
Multiple Neuroprotective Effects of Sulfasalazine Against NMDA, Free Radicals and Zinc.
, Society for Neuroscience 30th Annual Meeting
, Vol.26
, No.377.13
, pp.1013
-1013
(Nov, 2000)
-
[학술회의]
윤성화, 곽병주, 문호상, 안영민, 원석준, 유보름, 안정현, 이영애,
A Novel Neuroprotectant Preventing NMDA-, Free Radical-, and Zinc-neurotoxicity.
, Society for Neuroscience 30th Annual Meeting
, Vol.26
, No.377.14
, pp.1013
-1013
(Nov, 2000)
-
[학술회의]
윤성화, Nam seongil, 곽병주, 김수동, 문호상,
Syntheses and Neuroprotective Effects of Aspirin Analogs
, 220th Amnerican Chemical Society National Meeting
, pp.219
(Aug, 2000)
-
[학술회의]
윤성화, 황성관, A. Juhasz, K. Tatrai-Prokai, N. Bodor,
Soft Analogues of Bufuralol: Initial Pharmacological Evaluation
, 14th Annual Scinentific Meeting of American Society of Hypertension
, Vol.12
, No.4
, pp.114A
-114A
(May, 1999)
-
[학술회의]
Emy Wu, 윤성화, J. Wu, L. ProKai, N. Bodor,
Synthesis and Pharmacological Evaluation of a Brain-Targeted Chemical Delivery System of [Leu2, Pip3]-TRH
, PharmaceuticalResearch
, Vol.14
, No.11
(Nov, 1997)
-
[학술회의]
윤성화, 서승기, 이영희, 최승룡, 황성관,
Syntheses of 2-(3,5-Dimethyl-4-methoxypyridyl)benzothiazolidine Derivatives As A Potential H+/K+-ATPase Inhibitors
, Abstract of 213th ACS Natioanl Meeting
, Vol.1997
, pp.133
-133
(Apr, 1997)
- 국내학술발표
-
[학술회의]
신한호, 김욱, 노준기, 박주영, 윤성화, 윤주환, 이은영, 한지혜, 허성은,
Blockade of peripheral cannabinoid 1 receptors improves adipose inflammation, hepatic steatosis, and insulin resistance
, 제2회 생화학분자생물학회 에너지대사 연구분과 심포지엄
(Jun, 2016)
-
[학술회의]
이현정, 권정환, 윤성화, 이은화, 김균, 장희라,
효소분해시험과 미생물분해시험을 연계한 디클로페낙 및 대사산물의 환경거동평가
, 2011 대한환경공학회 국내 학술대회
(Aug, 2011)
-
[학술회의]
이현정, 권정환, 박성훈, 윤성화, 이은화, 김균, 장희라,
Microbial deconjugation of diclofenac glucuronide, a major phase II metabolite of diclofenac
, 2010 환경독성보건학회 추계학술대회
(Nov, 2010)
-
[학술회의]
윤성화, 박호준, 김정숙,
Rapid and selective reduction of the aromatic amide group by sodium acyloxyborohydride in the pesence of the aromatic ester group
, 대한화학회 제 94회 총회 및 학술발표회
, Vol.94
, No.1
, pp.378
(Oct, 2004)
-
[학술회의]
윤성화, 신영균, 이주영,
New Method for synthesizing 3-substituted-4-hydroxy-5-nitrobenzaldehyde from 3-substituted-D-4-hydroxyphenylglycine
, 대한화학회 제 94회 총회 및 학술발표회
, Vol.94
, No.1
, pp.378
-378
(Oct, 2004)
-
[학술회의]
김철, 김승현, 윤성화,
초임계 유체를 이용한 Peptide의 효소합성(II)
, 2000 가을 학술대회
, pp.3765
-3768
(Oct, 2000)
-
[학술회의]
김철, 김승현, 윤성화,
초임계 유체를 이용한 Peptide의 효소합성
, 2000 봄 학술대회
, pp.1221
-1224
(Apr, 2000)
-
[학술회의]
윤성화, 황성관, Attila Yuhasz,
Syntheses, Satabilities and Biological Evaluations of Soft Bufuralol Analogues
, 83rd Annual Meeting of the Korean Chemical Society
, Vol.1999
, pp.228
-228
(Apr, 1999)
-
[학술회의]
윤성화, Nicholas Bodor,
Target Brain Delivery of Peptide Analogues: Syntheses and Brain Delivery of TRH Analogues
, 제 1회 한국 펩타이드 심포지움
, Vol.1
, No.1
, pp.9
(Nov, 1997)
-
[학술회의]
윤성화, 문호상, 황성관,
Syntheses and Cytotoxicities of Four Stereoisomers of Muricatacin and It's Analogues
, Abstract of Annual Convention, 1997
, Vol.1997
, pp.385
-385
(Oct, 1997)
-
[학술회의]
윤성화, 김수동,
Pharmaceutical Formulation For Enhanced Bioavailability Of Ginkgobiloba Extract
, Abstract of Annual Meeting
, Vol.1997
, pp.352
-352
(Oct, 1997)
-
[학술회의]
윤성화, 황성관, 박장하,
Concise Synthesis of Substance S from Progesterone
, 77회 춘계 대한화학회 논문 초록집
, pp.120
-120
(May, 1996)
-
[학술회의]
윤성화, 서승기, 박상후,
Synthesis and Biological Evaluation of 2-(3,5-Dimethyl-4-methoxypyridyl)-benzothiazolines as a Novel class of Gasteric H/K-ATPase inhibitors
, 춘계 대한약학회 초록집
, pp.120
-120
(Apr, 1996)
-
[학술회의]
박규순, 윤성화, 최승룡, 양재영,
Synthetic Studies of 2,5-Disubstituted Bistetrafuran
(Oct, 1995)
-
[학술회의]
김동연, 윤성화, 배은형,
Synthesis of Pyrazolo-3-(H)-Quinolone Derivatives as (H+/K+)ATPase
, 약학회지
(Jun, 1995)
- 저서 및 번역
-
[저서]
윤성화, 김인규, 김정한, 노영쇠, 신대현, 조인호, 하현준,
유기화학 (Morrison & Boyd - 6th Edition)
(Mar, 1993)
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